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Resistance patterns to cephalosporins of members of the family enterobacteriaceae isolated from urinary tract infection | ||
| Mustansiriya Medical Journal | ||
| Article 1, Volume 6, Issue 2, 2006, Pages 37-44 | ||
| Authors | ||
| Abdul Wahab A.R. Hadi; Mithaq S. Al-Nassiry | ||
| Abstract | ||
| This study was conducted at the Al-Yarmouk Teaching Hospital to determine the resistance patterns to cephalosporins of members of the family Enterobacteriaceae isolated from urinary tract infections (UTIs). A total of 270 urine specimens were collected from February, 2004 to May, 2004. Escherichia coli was found to be the most organism, followed by Klebsiella spp. The results of susceptibility of isolates under study to different cephalosporins were moderately or highly resistant to many of the test agents. The observations on the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) for the cephalosporins explained the high level of resistance to cephalothin and cefaclor, and a moderate level of resistance to cefotaxime, ceftazidime and cefixime. The increasing MIC of cephalosporins, especially third generation, indicates decreasing susceptibility of these organisms to these types of β-lactam agents due to the production of extended spectrum β-lactamases (ESBLs). | ||
| Keywords | ||
| Cephalosporins; Enterobacteriaceae; UTI | ||
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