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A study of the immune response of Salmonella typhi - LPS in rabbits | ||
| journal of kerbala university | ||
| Article 1, Volume 2, Issue 4, 2006, Pages 109-116 PDF (0 K) | ||
| Author | ||
| Mahdi H. M.Al- Ammar | ||
| Abstract | ||
| The study included isolation of S. typhi from a diagnosed cases of typhoid patients, which dependent on the morphological and biochemical reactions in addition to the serological tests .LPS antigens were prepared and assuaged . as well as cell free culture filtrate antigen besides the ready prepared S. typhi agglutinogens. Such antigens were made available for plotting the immune status of the rabbits. In animals, S.typhi specific agglutinins titers(S.TH,S.TO) were measured and found to be within the range of 160-640 in peripheral blood respectively. The cellular immune response were determined by performing , leukocyte inhibition factor LIF. In case of S. typhi infection the LIF percentage raised up to 40% in systemic LIF when CFCF were used as a sensetizer . S. typhi immune protection was determined in animals ; the immune protection rate with LPS vaccine was 90% while the death rate was 10% . | ||
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