Vaginal leucocyte counts as indicator for cervical infections in women with bacterial vaginosis in Najaf, Iraq

Ph.D,; Mohammad Sadiq, Alaa

	Vaginal leucocyte counts as indicator for cervical infections in women with bacterial vaginosis in Najaf, Iraq
KUFA MEDICAL JOURNAL
Article 1, Volume 11, Issue 1, 2008, Pages 110-120
Authors
; Alaa Mohammad Sadiq
Abstract
The study analysed the relation of vaginal leucocyte counts to vaginal and cervical infections and to clinical manifestations in non-pregnant women diagnosed with bacterial vaginosis at Al-Zahraa teaching Hospital in Najaf governorate,Iraq. Of 300 women with bacterial vaginosis studied, the median age was 25 years and elevated vaginal leucocyte counts were associated with objective signs of vaginitis and cervicitis and also predicted candidiasis (OR 8, 95% CI 2.2 to 31), chlamydia (OR 3.1, 95% CI 1.4 to 6.5), gonorrhoea (OR 2.2, 96% CI 1.5 to 5.6), or trichomoniasis (OR 3.0, 95% CI 1.8 to 6.0). In general, as a screening test for vaginal or cervical infections, vaginal leucocyte count had very sensitivities and specificities, modrate positive predictive values, and high negative predictive values. An elevated vaginal leucocyte count in women with bacterial vaginosis was a strong predictor of vaginal or cervical infections. Vaginal leucocyte quantification may provide an alternative approach to assessing need for empirical therapy for chlamydia and gonorrhoea, particularly in epidemic zone.

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