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Relationship Between Atopic Dermatitis And BCG Vaccination | ||
| KUFA MEDICAL JOURNAL | ||
| Article 1, Volume 11, Issue 1, 2008, Pages 328-333 | ||
| Author | ||
| Asaad KT. Al-Yassen MSc | ||
| Abstract | ||
| The results reported in this paper are based on a case control study conducted in Basrah in 2005 to test the hypothesis that neonatal BCG vaccination decreases the subsequent development of atopic dermatitis. The study included all children with atopic dermatitis who attended the dermatological out patient clinic of Al – Sadr Teaching hospital, The total number of the cases was 252 children with atopic dermatitis, compared to a control group (350 child) who were chosen from the pediatric out patient clinic in the same hospital, The studied children or their parents were asked about the history of previous BCG vaccination and examined to detect the presence or absence of BCG scar, and the diameter of BCG scars was measured by a tape measure. The results of this study showed that the percentage of children with atopic dermatitis who had BCG scar diameter less than 1mm (negative BCG vaccine) was higher than that in the control group, and the risk of atopic dermatitis was 3.2 times more in children with negative BCG scar (diameter < 1mm) than in children with weak or positive BCG scar. The conclusion is that BCG immunization may provide protectiveness against atopic dermatitis. | ||
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