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A Non Invasive Evaluation Of Variability Of Intrarenal Blood Flow At Rest And During Exercise | ||
| KUFA MEDICAL JOURNAL | ||
| Article 1, Volume 11, Issue 1, 2008, Pages 366-383 | ||
| Authors | ||
| Akeel A.M. Hassan Zwain MBChB; PhD UK | ||
| Abstract | ||
| Under normal conditions, renal blood flow is controlled by intrinsic factors and factors include an auto regulatory mechanism, intrarenal renin-angiotensin mechanism and kinins. The critical extrinsic factors include the sympathetic nervous system (SNS) angiotensin II, dopamine, nitric oxide. ADH and ANP. These multiple factors work in concert to sustain renal blood flow and glomerular filtration regardless of wide variations in systemic arterial B.P. This investigation is devoted to assess the variability of intrarenal arterial blood flow at different regions of the kidney at rest and during dynamic exercise. The available Studies on this subject are few, conflicting and are adopting static exercise. The study is conducted on 10 male healthy individuals of age ranging between 18-30 years. The interlobar intrarenal arteries spectral parameters (PSV,MDV, RI, and VTI) at upper pole, mid pole and lower pole are obtained at rest in supine and upright positions and during performing supine exercise. A color Doppler U/S Siemens versa plus equipment with 2.5 MHz phased array probe or 3.5 MHz convex probe and a bicycle ergometer(E 315) to perform supine exercise were utilized for this purpose. It was shown that: 1-The over all intrarenal blood flow is significantly higher in supine position than that in upright position. 2-The intrarenal blood flow at mid pole is significantly higher than that of lower and upper poles. 3-There is no significant difference of intrarenal blood flow between the upper and lower poles. 4-There is significant decrease of over all intrarenal arterial blood flow during dynamic exercise; it is mainly the diastolic flow which is decreased. It was concluded that this technique would afford an indirect approach to study the renal artery blood flow. Further, this study would help to stand as a valuable method to assess renal perfusion. More over, it stands as an indirect method to assess renal artery stenosis before and after surgical revascularization. | ||
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