EFFECT OF SPICES MIXTURE ON BLOOD GLUCOSE AND LIPIDS PROFILE IN EXPERIMENTALLY - INDUCED OXIDATIVE STRESS FEMALE RABBITS

Abdul-khaliq Al-Jowari, Suha

	EFFECT OF SPICES MIXTURE ON BLOOD GLUCOSE AND LIPIDS PROFILE IN EXPERIMENTALLY - INDUCED OXIDATIVE STRESS FEMALE RABBITS
Iraqi Journal of Science
Article 1, Volume 53, Issue 2, 2012, Pages 279-284
Author
Suha Abdul-khaliq Al-Jowari
Abstract
The effect of spices mixture on blood glucose and lipids profile in oxidative stress rabbits was studied. Twenty female rabbits were randomly divided into four groups (five animals in each group). The first group was subjected to oxidative stress by the ad libitum supply of drinking water containing 0.5% H2O2. The second group was supplied with pellets containing 20% spices mixture. The spices mixture is composed of cinnamon, turmeric and cumin powder. The third group was subjected to H2O2 (0.5%) and supplied with pellets containing 20% spices mixture. The last group was considered as control and supplied with pellets and water. The period of experiment was lasted for 21 days. The results showed that there was a significant (P<0.05) decrease in glucose, cholesterol, triglyceride, LDL-C and VLDL-C concentration, except HDL-C concentration which increased significantly (P<0.05) in the groups exposed with spices mixture and spices mixture + hydrogen peroxide compared with stress animals. In conclusion, this study revealed that the supplementation of diets with moderate amounts of spices mixture might have some beneficial effects in oxidative stress conditions and reducing the risk of diabetes and atherosclerosis diseases through improving glucose and lipid metabolism. Therefore, the active materials in these natural plants might extract and use in diabetes and atherosclerosis drug industry from natural resources.

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