H. Al-Somaidaie, G., H. Al-Obaidy, F., H. AL-Jebory, S. (2012). Synthesis of Some 1 ,3 ,4- Oxadiazole and 1,2,4-Triazole Derivatives and Evaluation the Antibacterial Activity. , 3(3), 152-166.
Gazwan H. Al-Somaidaie; Fawzi H. Al-Obaidy; Shaymaa H. AL-Jebory. "Synthesis of Some 1 ,3 ,4- Oxadiazole and 1,2,4-Triazole Derivatives and Evaluation the Antibacterial Activity". , 3, 3, 2012, 152-166.
H. Al-Somaidaie, G., H. Al-Obaidy, F., H. AL-Jebory, S. (2012). 'Synthesis of Some 1 ,3 ,4- Oxadiazole and 1,2,4-Triazole Derivatives and Evaluation the Antibacterial Activity', , 3(3), pp. 152-166.
H. Al-Somaidaie, G., H. Al-Obaidy, F., H. AL-Jebory, S. Synthesis of Some 1 ,3 ,4- Oxadiazole and 1,2,4-Triazole Derivatives and Evaluation the Antibacterial Activity. , 2012; 3(3): 152-166.

Synthesis of Some 1 ,3 ,4- Oxadiazole and 1,2,4-Triazole Derivatives and Evaluation the Antibacterial Activity

karbala journal of pharmaceutical sciences
Article 1, Volume 3, Issue 3, 2012, Pages 152-166    PDF (0 K)
Authors
Gazwan H. Al-Somaidaie; Fawzi H. Al-Obaidy; Shaymaa H. AL-Jebory
Abstract
Some of hydrazone derivatives[2a-e] were prepared from the reaction of 2-phenyl acetic acid hydrazide[1] with different substituted benzaldehydes, then cyclization of hydrazones in glacial acetic acid and lead dioxide resulted into the formation of new 1,3,4-Oxadiazole derivatives [3a-e], Symmetrical 4-amino Triazole derivatives [5a-e] were prepared from reaction of 3,5-dibenzyl-4-amino 1,2,4-Triazole[4] with different substituted benzaldehydes to product new series of different Schiff bases [5a-e]. The prepared compounds were characterized by FT-IR, and UV spectroscopy, the melting points were determined and the purity and reaction time was checked by TLC, the biological activity was evaluated against different types of bacteria.
Keywords
Schiff bases; oxadiazole; Triazole; antibacterial activity; received; Accepted
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