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MUCO – CUTANEOUS CANDIDIASIS IN BASRAH INFANTS | ||
| basrah journal of science | ||
| Article 1, Volume 28, Issue 1, 2010, Pages 43-61 PDF (0 K) | ||
| Authors | ||
| K. K. Al-Rubaiy; and L. K. Muhsin; A. H. Al-Duboon | ||
| Abstract | ||
| A total of 185 clinical specimens were collected from 146 infants (65 males and 81 females) aged from 1 month to 2 years from Basrah General Hospital and Basrah Maternatily and children Hospital. The collected specimens were examind for etiologic agents by direct microscopy (KOH- mounting) and culture on suitable culture media. Five species of Candida were isolated and identified as: Candida albicans (66%), C. tropicalis (30%), C. krusei ( 2.4%), C. glabrata (1%) and Candida sp. ( 0.6%). The study was also conducted to determine the minimal inhibitory concentration (MIC) for the antifungals: clotrimazole, miconazole, nystatin, fluconazole and ketoconazole by the agar dilution method against the isolated species. Ketoconazole was the most effective antifungal inhibit 100% of the isolates at a concentration of 12.5 ug/ml. Clotrimazole came after Ketoconazole and Miconazole was the least effective drug. The activity of five antiseptics (phenol, Iodine, Povidone- iodine, gentian-violet and Lugol's-iodine) were also tested and the phenol was the most effective one against isolates of Candida. | ||
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