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Alkylation of 3-arylazetidin-2-ones by using Friedl Crafts reaction | ||
| basrah journal of science | ||
| Article 1, Volume 24, Issue 1, 2006, Pages 95-102 PDF (0 K) | ||
| Authors | ||
| ; ; | ||
| Abstract | ||
| 3-phenylthio-4,4-diethoxy carbonylazetidin-2-ones 6 have been conveniently Synthesized by reacting phenylthioacetyl chloride 2 with aryl substituted aminomalonates 3 under mild basic conditions. Thus using sulfuryl chloride 3-phenylthioazetidin-2-ones were transformed to-3-α -chioro phenylthio azetidin-2-ones, Alternatirely ,C-3 alkylation's of azetidin -2-ones using anisole in stannic chloride(SnCl4 ) | ||
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