Preliminary  Screening For Evaluation Activity Of Some Crude Plant Extracts Against Some Fungi Causes Superficial Mycoses

Abu- Mejdad, N.M.J.; Al-Meyah, A.R.A.A.; Al-Saadoon, A.H.

	Preliminary Screening For Evaluation Activity Of Some Crude Plant Extracts Against Some Fungi Causes Superficial Mycoses
basrah journal of science
Article 1, Volume 25, Issue 2, 2007, Pages 69-88 PDF (0 K)
Authors
N.M.J. Abu- Mejdad; A.R.A.A. Al-Meyah; A.H. Al-Saadoon
Abstract
The effect of cold aqueous and alcoholic exatracts of Caledula officinalis flowers , Alcea kurdica roots ,Ocimum basilicam leaves and Apium graveolens seeds on ten fungal isolates belinging to ten species isolated from patients with clinical symptoms of superficial mycoses studied . The results showed that the highest value of average rates of inhibitors diameters was 11.2 mm for the alcoholic extracts of Apium graveolens , while the lowest value was 0.1 mm for aqueous extracts of Ocimum basilicum leaves .Four types of cold &hot extracts using different solvents (namely water , 95% ethanol , acetone and hexane) for calendula officinalis and Apiam graveolens were prepared .The bioactivity of 500mg/ml concentration of each exctracts on four fungal isolates were tested .The result of these bioactivities showed that the fungus Aspergillus flavus has been less affected by these extracts where the average inhibition diameters was 1.79 mm , while the yeast candida albicans has been more affected where the average inhibition diameters was 13.5 mm.in addition ,the effect of the hot aqueous and alcoholic extracts of Calendula officinalis and Apium graveolens in the four isolates were highly significant , therefore the bioactivities of these extracts (with 500 mg/ml concentration ) against 14 fungal isolates were examined . Twenty two specific test with thin layer chromatography for all exctracts were done .

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