| During study (140) urine samples were examined from diabetic mellitus patient (70 diabeteic patient from type I and 70 diabeteic patient from type II ).They are 78 males and 62 females. All patients attending urine unit and from those setting at Marjan teaching hospital in Babylon province during period from October 2005 to the end of March 2006.Results have been compared with 40 urine samples belongs to healthy subjects (control). The results revealed that the percentage of bacterial infection associated with urinary tract for diabeteic patients (80.7%) ،while control (12.5%).Gram – negative bacteria, the main cause of infection, were constituted (77.9%) and included Escherichia coli (41.4%) , Klebsiella pneumoniae (28%) , Proteus mirabilis (5%) , Proteus vulgaris (2.1%),Enterobacter (1.4 %) Gram positive bacteria were constituted (2.8%) including Staphylococcus aureus(1.4 %) , Streptococcus pyogenes (1.4 %). The study revealed that the highest rate of infection (97.5 %) among(50 or more) year. According type of diabetic mellitus it was found that the highest rate of infection (93 %) was found among type I diabetic mellitus patient . Regarding sex factor , females revealed higher percentage (94 %) compared with males (71 %).The effect of some antibiotics on bacterial strain were performed, Gram negative bacteria were highly resistance to Ampicillin (99 %), Amoxycillin-clavulanic acid (96.2%),Cephalexin(94.3%), Cephalothin (68.2%),while lower percentage ( 52.3 %, 14.9%) recoreded with Gentamicin and Amikacin respectively |