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Type 2 Diabetic Nephropathy in Uncontrolled Patients Treated with Daonil® and Glucophage® | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 9, Issue 2, 2012, Pages 452-470 | ||
| Authors | ||
| Maha F.AL; ; Oda M. Yasser | ||
| Abstract | ||
| Type 2 diabetes mellitus is similar to type 1 and other forms of diabetes in that it is defined by high levels of plasma glucose and is associated with many long-term complications caused or enhanced by hyperglycemia and related metabolic abnormalities. Levels of glucose,glycohemoglobin(HbA1c),insulin, insulin resistance, ,creatinine , urea, eGFR, microalbominurea ,β2-microglobulin concentraions in sera ,blood, and urine of 298 patients diabetes mellitus treated with daonil(149) , glucophage (149) and 83 apparently healthy who served as control. The results showed a highly significant increase p<0.001 in glucose, HbA1c, insulin, insulin resistance , albumin , creatinine ,microalbominurea, concentrations in patient with diabetes mellitus treatment with daonil and glucophage (less and more than 5y) when compared to control group. Also a highly significant increase p<0.001 of urea, eGFR, β2-microglobulin concentrations(more than 5y).β2-microglobulin concentrations a significant increase p<0.05 in the urine(≤ 5y). | ||
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