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ADDICTION AND ANAESTHESIA | ||
| Basrah Journal of Surgery | ||
| Article 1, Volume 11, Issue 1, 2005, Pages 73-82 PDF (0 K) | ||
| DOI: 10.33762/bsurg.2005.55421 | ||
| Authors | ||
| Salam N Asfar; Nawfal A Mobark; Jasim M Salman | ||
| Abstract | ||
| Significant numbers of patients are seen for surgery and anesthesia with a history of chronic substance abuse. However, little is known about how these substances influences anesthetic physiology and pharmacology. Abuse of substances may involve a socially acceptable drug (e.g., alcohol, tobacco), a medically prescribed drug (e.g., diazepam), or an illegal substance (e.g., cocaine). Knowledge of a patient�s substance abuse prior to administration of analgesia or anesthesia may prevent adverse drug interactions, predict tolerance to anesthetic agents, and/or facilitate the recognition of drug withdrawal. As the neurobehavioral effects of cocaine may increase the likelihood that a user will receive violent fatal injuries and is more prone to have emergency surgery, so we stressed here on this substance. Cocaine abuse is associated with multi-target organ involvement, including the cardiovascular, respiratory, neurologic, and hematological systems. Its use during pregnancy is also an independent contributor to the risk of placental abruption, preterm labor and stillbirth. | ||
| Keywords | ||
| ADDICTION AND ANAESTHESIA | ||
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