R. Hamudi, S., Y. Yaseen, N., F. AL-Mosawy, W. (2011). Anti-tumor effect of Water and Alcoholic Extracts of Mushroom Agaricus bisporus against murine mammary adenocarcinomaimplanted mice. , 4(1), 68-76.
Salim R. Hamudi; Nahi Y. Yaseen; Wafaa F. AL-Mosawy. "Anti-tumor effect of Water and Alcoholic Extracts of Mushroom Agaricus bisporus against murine mammary adenocarcinomaimplanted mice". , 4, 1, 2011, 68-76.
R. Hamudi, S., Y. Yaseen, N., F. AL-Mosawy, W. (2011). 'Anti-tumor effect of Water and Alcoholic Extracts of Mushroom Agaricus bisporus against murine mammary adenocarcinomaimplanted mice', , 4(1), pp. 68-76.
R. Hamudi, S., Y. Yaseen, N., F. AL-Mosawy, W. Anti-tumor effect of Water and Alcoholic Extracts of Mushroom Agaricus bisporus against murine mammary adenocarcinomaimplanted mice. , 2011; 4(1): 68-76.

Anti-tumor effect of Water and Alcoholic Extracts of Mushroom Agaricus bisporus against murine mammary adenocarcinomaimplanted mice

Iraqi Journal of Cancer and Medical Genetics
Article 1, Volume 4, Issue 1, 2011, Pages 68-76
Authors
Salim R. Hamudi; Nahi Y. Yaseen; Wafaa F. AL-Mosawy
Abstract
This research was designed to study the effect of water and alcoholic crude extracts of Agaricus bisporus in vivo. Therapeutic effect of both extracts was studied in murine mammary adenocarc- inoma- implanted mice after
(I.P) administration of watery extract at concentrations of (333.3, 500, 666.6 mg/kg) and alcoholic extract at
concentrations of (500, 1000, 1500 mg/kg) for 30 days alternatively.
The results revealed significant reduction in the tumor volume weather in those treated with watery extract 87.10%, or
those treated with alcoholic extract 87.98%, particularly at the concentration of 666.6 mg/kg and 500 mg/kg respectively.
Histopathological study showed necrosis and infiltration of inflammatory cells within fibrous encapsulated tumor
mass.
Keywords
Agaricus bisporus; Intra; peritoneum
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