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Effect of Different Concentrtions of Water Extract of Oyster Mushroom on the Growth of Cancer Cells In Vitro | ||
| Iraqi Journal of Cancer and Medical Genetics | ||
| Article 1, Volume 4, Issue 2, 2011, Pages 72-76 | ||
| Authors | ||
| Abdulilah M. Abdulhadi; Jabbar H. Sallom; Shalal M. Hassein | ||
| Abstract | ||
| The spawn of the oyster mushroom Pleurotus ostreatus ( Jaq: Fr. ) was added to a sterilized and moist wheat straw and incubated at 25 ± 2 ºC for one month then transferred to the growth room at 25 ± 2ºC and 80-90% humidity and light was raised to 400 Lux. The fruiting bodies were dried and used for water extract of oyster mushroom. The extract was added to the line of cancer cells Hep-2 at the following concentration: 0.0 , 15.6 , 31.25 , 62.5 , 125 , 250 , 500 , 1000 micro gram / ml.The Results showed that the water extract of the oyster mushroom inhibited the growth of cancer cells at the concentration of 500 and 1000 microgram/ml after 24 hour of incubation at 37ºC. Increasing the incubation time to 48 hours increased the inhibition effect of the mushroom extract at all the concentrations used, while the growth of the untreated cells was not inhibited.Our conclustion the extract have inhibition effect on cell growth depend up on the time of exposure and concentration. | ||
| Keywords | ||
| oyster mushroom; Hep | ||
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