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Cytotoxicity and Antibacterial Effect of 2-(2-hydroxy naphthylazo) phenyl mercuric chloride and 4-(2-hydroxy naphthylazo) phenyl mercuric chloride against some bacterial isolates in vitro | ||
| Journal of Basrah Researches (Sciences) | ||
| Article 1, Volume 36, Issue 2, 2010, Pages 65-69 PDF (0 K) | ||
| Author | ||
| Shaker A. N. Aljadaan and Eiman A. Saeed | ||
| Abstract | ||
| The 2-(2-hydroxynaphthylazo) phenyl mercuric chloride and 4-(2-hydroxynaphthylazo) phenyl mercuric chloride were evaluated for their biological activity against standard strains of Staphylococcus aureus ATCC25923 and Ecsherichia coli ATCC 25922. The results showed that there is a potent antibacterial activity for these compounds. Minimal inhibitory concentration was determined for two compounds, it was 20µg/ml, 40µg/ml for Staph. aureus, and 50µg/ml, 60µg/m for E. coli respectively. Cytotoxicity assay was carried out against human red blood corpuscles, the two compounds exhibited a toxic effect in all used concentrations. | ||
| Keywords | ||
| Cytotoxicity; Inhibitory effect; Toxic effect; antibacterial activity | ||
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