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EFFECT OF HALOPERIDOL ON SELECTED | ||
| Journal Of Wassit For Science & Medicine | ||
| Article 1, Volume 2, Issue 2, 2009, Pages 127-137 | ||
| Authors | ||
| Atta Gitti Allawi Consultant Physician; Jabbar Y.AL-Mayah; | ||
| Abstract | ||
| The present study was conducted to assess the effects of haloperidol (psychiatric drug ) on some oxidative stress parameters (GSH and lipid peroxidation product MDA) and it's relation to the dopamine level in rats' brain. Twenty-four male Sprague- Dawely rats were enrolled in this study. They were randomly separated into three groups, eight rats in each group: Group 1, (normal control group), eight rats were put on normal chow diet for 45 days from which the baseline value of selected parameters were measured. Group 2 (self control group) on distilled water orally administered by stomach tube for 45 days. Group 3 on Haloperidol 1 mg/kg orally administered by stomach tube for 45 days. | ||
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