The assessment of gingival changes in children with acute Lymphoblast leukemia before and after chemotherapy - clinical study-

M.Sc,; Likaa M. Ibrahem B.D.S, Dr.; M.Sc,; Mourog Al-Ani B.D.S, Dr.; Ayade Khalil B.D.S, Dr.

	The assessment of gingival changes in children with acute Lymphoblast leukemia before and after chemotherapy - clinical study-
MUSTANSIRIA DENTAL JOURNAL
Article 1, Volume 3, Issue 4, 2006, Pages 379-385
Authors
; Dr. Likaa M. Ibrahem B.D.S; ; Dr. Mourog Al-Ani B.D.S; Dr. Ayade Khalil B.D.S
Abstract
Background: The aim of this study was to asses the gingival changes in children with Acute Lymphoplastic Leukemia (ALL) before and after treatment. Material and method: The sample consist of (15) children with ALL (the age range was 7-13 years with an average of 10 years of age). They were newly diagnosed. The patients were examined three times: 1st visit , before starting with chemotherapy (day 0) , 2nd visit , after 15 days from using chemotherapy (day 15) , 3rd visit after 30 days from using chemotherapy ( day 30 ) . The examination included clinical parameters namely plaque index (PL.I),gingival index (G.I), assessment of gingival enlargement , collection of gingival cervicular fluid (G.C.F) , bleeding point index and Hematological parameters namely : white blood cells count (WBC count),platelets count and hemoglobin level in blood (HB). Result: There was significant difference (decrease) occurred in G I and point index ( p < 0.05 ) in day 30 in compare to day 0. The intimate correlation of clinical parameter correlation of clinical parameter (C P) in day 0 was with systemic factor while in day 30, was with local factor (plaque) Conclusion: There was a significant improvement in gingival health status in day 30 compared to day 0 , the intimate correlation of ( CP ) in day 0 was with systemic factor but in day 30 was with local factor with less extend to systemic factor.
Keywords
Key Word; chemotherapy treatment; clinical parameters

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