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SPECTROPHOTOMETRIC DETERMINATIONOF TETRACYCLINE IN SOME PHARMACEUTICALPREPARATIONS | ||
| Journal of Basrah Researches (Sciences) | ||
| Article 1, Volume 32, Issue 1, 2006, Pages 43-48 PDF (0 K) | ||
| Authors | ||
| Z.T.AL-Abdullah and; ; | ||
| Abstract | ||
| This paper briefly describes a simple spectrophotometric method for the determination of tetracycline in pharmaceutical preparation . The method is based on measurement of the absorbance of tetracycline- cerium(IV)complex at 430 nm in 1M sulphuric acid solution. Calibration graph for tetracycline was obtained over the range of 50-350 µg.ml- 1 The detection limit (2x noise) is 0.0025 µg.ml- 1 and with R.S.D for 5 replicate 0.03% . This method allowed the determination of tetracycline in pharmaceutical preparations with a satisfactory accuracy when comparing it with official BP method. | ||
| Keywords | ||
| Spectrophotometry; cerium; Tetracycline; Pharmaceutical Preparation | ||
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