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The activity of 1,3,4 Thiadiazole Derivatives on the soluble oils | ||
| Journal of Petroleum Research & Studies | ||
| Article 1, Volume 190, Issue 2, 2011, Pages 59-88 | ||
| Author | ||
| Khalid W.Y.Zain Alabdeen | ||
| Abstract | ||
| Abstract: That Thiadiazoles derivative is biologically active as antimi-crobial agents in cooling fluids. Derivatives of 1, 3, 4- thiadiazole have prepared: 1- 2-amino-3-[(2-amino-1, 3, 4-thiadiazol-5-yl) dithio] propanoic acid. 2- 2-(2-Carbethoxyamino-1, 3, 4-thiadiazol-5-yl)-thio acetic acid. 3- [(5-amino-1,3,4-thiadiazol-2-yl) dithio] acetic acid The synthesized compounds have been used as antimicrobial against the microorganisms which have been found in the cooling fluid of industrial purposes by using media culture the results showed that the compounds 1 and 3 are relatively highly active in killing bacteria from the compound 2. The pH of the cooling fluid sam-ples had been measured after the addition of salt media as well as the inhibitors (1,2,3) the results of pH measurement revealed that the compounds 1,2 and 3 exhibit high activity to inhibit the growth of bacteria. The turbidity for such media and inhibitors has also been measured and the results indicated that 1,2 and 3 have given low turbidity to inhibit the bacteria or the micro-organisms that grow in the cool-ing fluid. | ||
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