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Helicobacter Pylori Associated with Peptic Ulcer Disease and Chronic Antral Gastritis in Diwania City.…. | ||
| Kerbala Journal of Medicine | ||
| Article 1, Volume 2, Issue 4, 2009, Pages 382-386 PDF (0 K) | ||
| Author | ||
| Dr. Ali M. Al-Yassin | ||
| Abstract | ||
| aim: To study the prevalence of Helicobacter Pylori organism as a cause of peptic ulcer disease and chronic antral gastritis in patients in Diwania city. Methods: In this study 90 patients patients complaining from classical symptoms of chronic dyspepsia including upper abdominal pain or discomfort, often accompanied by bloating, abdominal distention, nausea, or early satiety were included in this study. Peptic ulcer and antral gastritis are diagnosed on both endoscopic findings and histological results of biopsy . 4–6 punch biopsies were taken from gastric antrum in all the individuals and in case of gastric ulcer an additional biopsy was taken from the edge of the ulcer to exclude its malignant nature. Helicobacter pylori (H. pylori) organism was diagnosed using Histology (using Giemsa Stain). Histological diagnosis of H. pylori was taken as the “gold standard” for the presence of H. pylori organism. Histological diagnosis of gastritis was made using Hematoxylin and Eosin Stain and the gastritis was classified as active chronic gastritis and superficial chronic gastritis. Results: From 90 patients were included in this study, 50 patients were proved to have peptic ulcer disease, 45(90%) of them have positive results of H pylori while 40 patients proved to have chronic antral gastritis, 33(82.5%) of them were positive for H. pylori on histological examination. Conclusion: A highly significant association between H. pylori infection with peptic ulcer disease patients and chronic antral gastritis in Diwaniya city. List of abbreviations PU = peptic ulcer PUD = peptic ulcer disease CAG = chronic antral gastritis OGD = oesophagogastrodoudenscopy DU = duodenal ulcer | ||
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