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Serum Immunoglobulin Level Derangements in Chronic Lymphocytic Leukemia, Hodgkin's Disease and Non- Hodgkin's Lymphoma | ||
| Kerbala Journal of Medicine | ||
| Article 1, Volume 2, Issue 4, 2009, Pages 452-462 PDF (0 K) | ||
| Author | ||
| Dr. Talib H. Kammona | ||
| Abstract | ||
| oBjective: to compare the degree of immunoglobulin derangement "hypo or hypergammaglobulinaemia" among patients with cll, nhl, and hd. Design: forty three patients with hematologic malignancies attended hematology and oncology unit in al-sadr teaching hospital in najaf city between february and august 2007, were evaluated for their serum igg, igm, and iga level with a comparable number of healthy adult controls. Sixteen patients with cll, thirteen patients with nhl, and fourteen patients with hd were included in this study. Results: there is a significant alteration in the level of immunoglobulin among patients with hematologic malignancies, with a reduced level seen in patients with cll and nhl, and an elevated level is seen in patients with hd. Conclusion: immunoglobulin derangement is a common problem in patients with cll, nhl and hd. Recommondations: larger number of patients, with extension of the study to include igg subsets is needed for good outcome and better results. | ||
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