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Electrolytes & [H+] Disturbances in Peptic Ulcer Patients | ||
| Kerbala Journal of Medicine | ||
| Article 1, Volume 2, Issue 4, 2009, Pages 447-451 PDF (0 K) | ||
| Author | ||
| Monem Alshok | ||
| Abstract | ||
| in the body even a very small pH changes are important and result in change in body physiology . We describe in our study the presence of alteration in electrolytes and acid-base status in patients with peptic ulcer disease. The study was carried out over a period of three years. 273 patients with peptic ulcer disease diagnosed on endoscopy , of these 228 duodenal ulcer and 45 gastric ulcer , in addition 84 subjects were considered as a healthy control . 20 ml of gastric juice obtained for analysis and 5 ml blood sample were taken and pH determination and[ H+ ]estimated by electric sensitive method including the use of electronic sensitive pH – meter. The pH – electrode was initially calibrated in buffer solution of pH 7 ( Ian 1969 ). Also the total acidity of gastric effluents were estimated by titration to pH 7 with 0.1 NaOH. The K+ and Na+ concentrations determined by using flame photometric method ( Sood 1987) The results of the study show that DU patients had significantly lower gastric secretion pH and higher H+ concentration in the blood than normal control subjects and total acidity of gastric secretion also was higher than control. | ||
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