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Prevalence of Endocrine Disorders among Iraqi Women with Menstrual Disturbances | ||
| Kerbala Journal of Medicine | ||
| Article 4, Volume 3, Issue 7, 2010, Pages 889-896 PDF (0 K) | ||
| Author | ||
| Hussein Kadhem Al-Hakeim | ||
| Abstract | ||
| background and Objectives: The main causes of menstrual cycle disturbances are classified as hormonal abnormalities, structural abnormalities, bleeding diatheses, anovulation, polycystic ovary (PCO), obesity and miscellaneous. In this work, the prevalence of endocrine disorders in Iraqi women with menstrual disturbances was estimated. Patients and Methods: One hundred Eighteen females with menstrual disturbances (delay>10 days occasionally) were included in this study in addition to thirty seven control women. They were attending to the gynecological clinics for regulation of menstruation cycle. The study excluded any women taking steroid hormones, neuroleptics, anticoagulants and cytotoxic agents that frequently lead to menstrual disturbances. Luteinizing hormone (LH), follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH), prolactine, total testosterone, estradiol (E2) and progesterone were estimated in the second day of the menstrual cycle using ELISA technique using a ready for use kits. Results: The endocrine disorders in menstrual disturbances in the Iraqi women under study were: 16.1% hypothyroidism, 3.4% hyperthyroidism, 3.4% type 1 diabetes mellitus, and pituitary tumor was observed in 1.6 % of patients. Additionally, there is a high prevalence of patients with POCS cases and a high significant increase in the mean of BMI in the patients when compared with the control women. Conclusion: Surprisingly, the most common endocrine disorder in the women with menstrual disturbances group was hypothyroidism. Additionally the PCO is common in these women. The prevalence of endocrine disorders in irregular women in Iraq was lower than the other countries and the type of prevalent endocrine disorders is different | ||
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