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Treatment Failure of Tuberculosis in Diabetic Patients | ||
| Kerbala Journal of Medicine | ||
| Article 13, Volume 2, Issue 5, 2009, Pages 630-634 PDF (0 K) | ||
| Authors | ||
| Mosa Ismail Al-Karawi; Sadiq Al-Muhana | ||
| Abstract | ||
| background: despite the availability of effective treatment , tuberculosis continues to infect a large number of patients . Treatment failure is one of the major problems in the TB control programs. Objective: To evaluate the treatment failure in tuberculosis patients with diabetes mellitus. Patient & Method: In this retrospective study that extended from August 2007 to August 2008, 69 patients with tuberculosis and diabetes mellitus and 105 patients with T.B. only, were included .All patients were from Al-Najaf and treated by ( Direct Observe Therapy programs)D.O.T.s .The patients are evaluated by the following data :- demographic data, site of disease by CXR, date of initial diagnosis of TB., purified protein derivative (tuberculin test ) results , smoking history. The data were analyzed by using the statistical package social system (SPSS) and P. value <0.05 was regarded as statistically significant. Results: Patients with tuberculosis and diabetes mellitus were 69 (58 male and 11 female) equal to(40%) of the total patients were treated with direct observe therapy (D.O.T.s) program, the treatment failure were 18 patients (12 male and 6 female) equal to (26%) of patients in this group. Patients with tuberculosis only were 105 (89 male and 16 female) and equal to (60%) of the total patients were also treated with( D.O.T.s ),and the treatment failure were 10 patients ( 7 male and 3 female) that equal to (1o%) of patients in this group. The age group(30-50) years had a higher failure rate in both groups . The failure was more in males, smokers, with tuberculin test negative, and in upper lobe lesions. Conclusion: There was a significant association between diabetes and failure in TB. treatment, which is more in male, smoker , in those have negative tuberculin test , and in TB of upper lobe of the lung . | ||
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