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Vitamin D Level In Patients With Multiple Sclerosis In Comparison With Healthy Controls…..... | ||
| Kerbala Journal of Medicine | ||
| Article 27, Volume 2, Issue 5, 2009, Pages 751-757 PDF (0 K) | ||
| Author | ||
| Sana Abdul-Razak Ibraheem | ||
| Abstract | ||
| background: Multiple sclerosis is a chronic, immune – mediated inflammatory and neurodegenerative disease of the central nervous system (CNS). The prevalence of multiple sclerosis is highest where environmental supplies of vitamin D are lowest. Vitamin D is a steroid aid to maintain the normal level of calcium in the circulation, enhancing immune function, and may protect people from multiple sclerosis. Objective: To evaluated the effectiveness of vitamin D and calcium level in patients with multiple sclerosis. Design: Two groups, healthy and patients based in hospital. Setting: Both healthy and patients of the Iraqi population in Al-Hakeem hospital in AL-Najaf city. Population: 36 patients (11 male, 25 female), and 36 healthy (15 male, 21 female). Methods: Study was carried out in the department of biochemistry, Collage of Medicine, Kufa University in period from February to August 2005. The samples was measured by the high performance liquid chromatography (HPLC) technique. This technique was of choice in measuring the low levels of vitamin D in sera. Results: The normal values of vitamin D levels were in 19.21 ng/ ml ±5.51, and calcium levels were 10.79 mg / dl ± 1.19 in both sexes (males and females). The result were taken from also showed that a first group a high significant decrement (P< 0.01). In serum of thirty-six patients affected with multiple sclerosis, the vitamin D level average in this group were 6.46 ± 0.91 ng / ml, and calcium level were 8.69 ± 1.85 mg / dl. | ||
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