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• Evaluation of Serum Cystatin C in Iraqi Cardiovascular Patients | ||
| Kerbala Journal of Medicine | ||
| Article 1, Volume 4, Issue 10, 2011, Pages 1063-1066 PDF (0 K) | ||
| Author | ||
| Shaimaa S. Mutlak | ||
| Abstract | ||
| background: Cystatin C has been reported to be a potent predictor of increased cardiovascular disease mortality. Serum Cystatin C may have a stronger association with mortality and cardiovascular disease than serum Creatinine in patients with normal or mildly reduced kidney function. Objectives: The aim of this study to 1- Determine the prognostic value of cystatin C in patients with cardiovascular disease (CVD) and compare the observed value with that obtained for healthy controls. 2- Study the correlation between serum cystatin C and creatinine in cardiovascular disease patients. Patients and Methods: The prospective study included thirty (30) patients admitted to hospital with cardiovascular disease (CVD) slected from Baghdad teaching hospital and twenty-one (21) healthy individuals were included in this study. Fasting serum cystatin C and creatinine were measured in all patients and controls. Results and Discussion: A significant increased in the level of serum cystatin C concentration was observed in patients with (CVD) as compared with the control group. Conclusion: Cystatin C is a prognostic biomarker of CVD. A graded association exists between higher serum Cystatin C and increased CVD prevalence in patients without chronic kidney disease (CKD). | ||
| Keywords | ||
| Cystatin C; Cardiovascular disease; creatinine | ||
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