- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
• Oxidative stress and Lipid peroxidation in patients with Multiple | ||
| Kerbala Journal of Medicine | ||
| Article 1, Volume 4, Issue 10, 2011, Pages 1073-1076 PDF (0 K) | ||
| Authors | ||
| Halla G. AL-Gebouri; Hedef EL-Yassin | ||
| Abstract | ||
| Back ground: multiple sclerosis (MS) has a much higher incidence among Caucasians that in any other race. Females are much more susceptible than males and white females living in colder weather areas are much more susceptible than those living in warmer areas. Oxidative stress means an alteration in the delicate balance between free radicals and the scavenging capacity of antioxidant enzymes in favor of free radicals in the body system. Objective: To evaluate and compare the antioxidants and lipid peroxidation in patients with MS and healthy control. Patients and method: The study has included thirty patients with MS (16 females and 14 males) and thirty healthy subjects. The subjects were selected from people attending the out patients clinic of Baghdad Teaching Hospital in Medical City. Laboratory parameters included were: uric acid, albumin, and caeruloplasmin, total thaiol, malondiaaldehyde (MDA) and peroxinitrate (ONOO¯). Results: MDA and ONOO¯ levels in serum of patients with MS were significantly higher than in the control group. While the levels of GSH, CP, albumin, uric acid, iron, copper and zinc in serum of patients with MS were significantly lower than in healthy control. Conclusion: Oxidative stress may have a role in the pathophysiology of multiple sclerosis syndromes. | ||
| Keywords | ||
| lipidperoxide; ONOO; GSH; Uric acid; Albumin; multiple sclerosis | ||
|
Statistics Article View: 39 PDF Download: 31 |
||