Dawwas Matter Al-Maliki, A., Latif Shihab Al-DeenHusham Mnahi Talib Al- Ryhani, N. (2011). Isolation and Identification of Phenol -2- methoxy-3-(2-propenyl) ,Eugenol and Caffeic Acid Compounds from Prosopis farcta Fruits and Study of Their Activity as Drugs Against Pathogenic Bacteria of Urinary Tracts. , 37(5), 134-155.
Abbas Dawwas Matter Al-Maliki; Nezar Latif Shihab Al-DeenHusham Mnahi Talib Al- Ryhani. "Isolation and Identification of Phenol -2- methoxy-3-(2-propenyl) ,Eugenol and Caffeic Acid Compounds from Prosopis farcta Fruits and Study of Their Activity as Drugs Against Pathogenic Bacteria of Urinary Tracts". , 37, 5, 2011, 134-155.
Dawwas Matter Al-Maliki, A., Latif Shihab Al-DeenHusham Mnahi Talib Al- Ryhani, N. (2011). 'Isolation and Identification of Phenol -2- methoxy-3-(2-propenyl) ,Eugenol and Caffeic Acid Compounds from Prosopis farcta Fruits and Study of Their Activity as Drugs Against Pathogenic Bacteria of Urinary Tracts', , 37(5), pp. 134-155.
Dawwas Matter Al-Maliki, A., Latif Shihab Al-DeenHusham Mnahi Talib Al- Ryhani, N. Isolation and Identification of Phenol -2- methoxy-3-(2-propenyl) ,Eugenol and Caffeic Acid Compounds from Prosopis farcta Fruits and Study of Their Activity as Drugs Against Pathogenic Bacteria of Urinary Tracts. , 2011; 37(5): 134-155.

Isolation and Identification of Phenol -2- methoxy-3-(2-propenyl) ,Eugenol and Caffeic Acid Compounds from Prosopis farcta Fruits and Study of Their Activity as Drugs Against Pathogenic Bacteria of Urinary Tracts

Journal of Basrah Researches (Sciences)
Article 1, Volume 37, Issue 5, 2011, Pages 134-155    PDF (0 K)
Authors
Abbas Dawwas Matter Al-Maliki; Nezar Latif Shihab Al-DeenHusham Mnahi Talib Al- Ryhani
Abstract
propenyl) were isolated and identified from Prosopis farcta fruits . The is recommended to use
the phenolic compounds as herbal therapeutic substituents for treatment of urinary tracts
infections instead of antibiotics physical and chemical methods were used in identification such as
UV-vissible and infrared spectra , thin layer chromatography , column chromatography , fanctional
groups test, gas-chromatography-mass spectrum and melting point . The medicinal The
phenolic compounds (caffeic acid,eugenol and phenol -2- methoxy -3-(2-activity for compounds
isolated with concentration ( 150 mg / ml ) , were studied against five types of pathogenic bacteria of
urinary tracts infections, are Escherichia coli , Staphylococcus aureus , Proteus sp. , Klebsiella sp.
and Pseudomonas aeraginosa . The minimal inhibitory concentration and cellular toxicity of
these compounds , were determined , also the medicinal activity of isolated phenolic compounds ,
was compared with some antibiotics such as ampicillin , cephlaxin , ciprofloxacin , streptomycin
and tetracycline . The phenolic compounds showed that they have a highest medicinal effect
for inhibition of bacteria growth than antibiotics . It was found that isolated compounds have no a
toxic effect against red blood cells of human . As a result , it is recommended to use the
phenolic compounds as herbal therapeutic substituents for treatment of urinary tracts infections
instead of antibiotics having side effects but this work demands further clinical and
pharmaceutical studies .
Keywords
Prosopis farcta; caffeic acid; phenol; Methoxy; propenyl; Eugenol
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