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Unconjugated Neonatal Hyperbilirubinemia: Evaluation and Treatment | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 23, Issue 3, 2010, Pages 165-168 | ||
| Authors | ||
| Nahla I. Al-Gabban; Haider Nadhim Abd; Essam Ahmed Abd | ||
| Abstract | ||
| Background: neonatal jaundice is a common problem with a lot of mistakes that happen during its management, requiring the doctors and medical staff to follow a certain guidelines for dealing with this disease to obtain the best results. Objective: (1) to study some of the causes of neonatal unconjugated hyperbilirubinemia. 2) To discuss the causes and proper line of therapy. (3) To discuss the complications associated with the management of this problem. Methods: The study included 100 neonates aged 0-14 days with hyperbilirubinemia who were admitted to the Central Teaching Hospital for Children in Baghdad during the period from 1st of February – 1st of June2008. Term infants with TSB ≥ 22mg/dl were treated by exchange transfusion and phototherapy (Group A, 38 patients). Those with TSB level from 13-22mg/dl were treated by phototherapy only (Group B, 62 patients). These decisions were taken mostly according to the TSB level, gestational age and body weight. Results: Twenty five percent of cases had hemolytic cause (Rh-isoimmunization, 13%; ABO-incompatibility, 10%; G6PD-deficiency, 2%). Other causes include: pretermaturty, 33%; sepsis, 8%; congenital CMV infection, 1%; and there were 33 (33%) infants had no evidence of hemolysis or other serious problems. There were 2 deaths in our study after exchange transfusion due to septicemia. The mortality rate after exchange transfusion in the study was 4.4% (from total number of exchange transfusion processes). Conclusions: There appears to be lack of a protocol for the management of cases of neonatal unconjugated hyperbilirubinemia. The cause of hyperbilirubinemia is usually overlooked. Key words: Neonate, hyperbilirubinemia, Jaundice. | ||
| Keywords | ||
| Neonate; hyperbilirubinemia; jaundice | ||
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