Measurement of Total Antioxidant Status (TAO) and Superoxide dismutase (SOD), Catalase (CAT) Enzymes in Petrol Station workers

A. Mahmood, Noah; H. Jaafar, Teebaa; Alaamier,; A, Rasha; S. Zaki, Zeena

	Measurement of Total Antioxidant Status (TAO) and Superoxide dismutase (SOD), Catalase (CAT) Enzymes in Petrol Station workers
IRAQI JOURNALOF COMMUNITY MEDICINE
Article 1, Volume 24, Issue 2, 2011, Pages 120-124
Authors
Noah A. Mahmood; Teebaa H. Jaafar; ; Rasha A; Zeena S. Zaki
Abstract
Background: Total antioxidant status, superoxide dismutase (SOD) and Catalase (CAT) are antioxidant defensive enzymes that catalyze the reduction of reactive oxygen species (ROS) to non harmful substance. Aim: The study focuses on the serum super oxide dismutase enzyme level, CAT level and total antioxidant status in petrol station workers to detect any imbalance between aggressive and defensive factors. Materials & Methods: the study included 40 workers and 20 healthy subjects in a comparative analysis. (TAO), serum (SOD) and (CAT) levels were measured for study subjects. Results: Statistical analysis of serum antioxidant enzymes level and antioxidant status revealed a significant increase in SOD, CAT of worker groups (p.≥0.05), and (P.≥0.01) respectively. The TAO was significantly increased (p.≥0.001). The increased of serum SOD, CAT levels and the TAO can be explained on the basis of alteration on enzymes activity, which may lead to disturbance in homeostasis of antioxidant/oxidant balance. Conclusions: TAO, Catalase and Superoxide dismutase enzymes can used as a biomarker of enzymatic alteration in different diseases. Key wards: Total Antioxidant Status, Super Oxide dismutase, Catalase, Petrol Station Workers.
Keywords
Total Antioxidant Status; super oxide dismutase; catalase; Petrol Station Workers

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