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Lymphocytes Subset Phenotypes in Patients with Visceral Leshmaniesis | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 24, Issue 4, 2011, Pages 308-313 | ||
| Author | ||
| Jabbar Resen. Zangor Al-Autabbi | ||
| Abstract | ||
| Background: Visceral leishmaniasis is an endemic protozoan disease in Iraq Recovery from this disease confers a solid and permanent immunity. Objective: Determining the type of lymphocyte phenotype by using; monoclonal antibodies against (CD 4, CD8). Patients and methods: Indirect immunofluorescence technique analysis was performed to detect the percentage of CD4, CD8 and CD4/CD8 ratio positive lymphocytes. Results: Our results showed that the patients groups have decrease in both the percentage of CD4 cells &CD4/CD8 ratio and increase in the percentage of CD8. Follow up of patients after treatment showed a significant increase in the percentage of CD4, CD4/CD8 ratio but they were still lower than their normal range. Conclusion: CD4/CD8 ratio is reversed in VL infection then increase after treatment but it was less than its normal range. Key words: CD-Markers profile, leishmania donovani, amastigote form. | ||
| Keywords | ||
| Markers profile; leishmania donovani; amastigote form | ||
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