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Biochemical and demographical study of lipid profile in sera of patients with gallstone | ||
| Iraqi Journal of Science | ||
| Article 1, Volume 53, Issue 4, 2012, Pages 760-768 | ||
| Authors | ||
| Sabah Abaas Al-Ardhi; Narjis Hadi Al-Saadi | ||
| Abstract | ||
| Thirty patients with gallstone [aged 25-55 years]and thirty age-and sex-matched healthy subjects as control group were involved. Those patients were intended to undergo surgical removal of gallbladder in the surgical ward- Al Sadder Teaching Hospital and AL-Hakeem Hospital in Najaf city during the period from July/2009 to December /2009. The proportion of female was [86%] compared to the male t [14%]. The ratio of female: male was 5:1. Blood samples were obtained from all patients prior to surgery. Serum was obtained by usual methods and analyzed for lipid profile test [total cholesterol [TC], triglyceride [TG], high density lipoprotein- cholesterol [HDL-C], low density lipoprotein cholesterol [LDL-C] and very low density lipoprotein cholesterol [VLDL-C]}. The results showed that there were no significant differences between gallstone patients and control regarding HDL-C [p>0.05] but there was highly significant [p>0.05] difference in the concentrations of total cholesterol [TC], triglyceride [TG] and VLDL-C comparing with the control group. The study also showed that the sex has a significant effect [p>0.05] on the levels of TC, LDL-C, and VLDL-C in sera of patients with gallstone whereas, non significant sex variation had found with respect to HDL-C level. On the other hand, it was also found that there was a significant p>0.05 ] age variations with respect to serum levels of TC, TG and VLDL-C with effect with respect to both HDL-C and LDL-C levels in sera of patient with gallstone. Additionally, all items of lipid panel found to be significantly [p>0.05] varied with respect to the BMI. Similarly, smoking was found to be important cause and revealed a significant [p>0.05] difference regarding all parameters- but not LDL-C of lipid components. The objective of this study was to estimate the serum lipid profile, in sera of patients with gallstone and investigate their relationship with demographic factors. | ||
| Keywords | ||
| gallbladder; Gallstone; lipid profile test | ||
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