Antagonstic Effect of Lactobacillus Fermentum Supernatant AgainstEnterococcus Faeciumand Enterococcus Faecalis In Vitro

H. Mahdi, Likaa

	Antagonstic Effect of Lactobacillus Fermentum Supernatant AgainstEnterococcus Faeciumand Enterococcus Faecalis In Vitro
Journal of the Faculty of Medicine
Article 1, Volume 54, Issue 2, 2012, Pages 154-157
Author
Likaa H. Mahdi
Abstract
Background:Lactobacillus fermentum selected as an alternative treatment to prevent or treat urogenital infection based on their probiotics properties and production of bacteriocins. Objective: The present work was done to study the inhibition activity of L. fermentum cell free supernatant against urogenital pathogens Enterococcus faecium and Enterococcus faecalisinvitro. Materials and methods: L.fermentum isolates have been collected from vaginal swabs . A supernatant of these isolates has been prepared and its antibacterial activity against 3 isolates of E.faecium and 3 isolates of E.faecalis has been studied. Results: Different concentrations have been prepared and the most effective one was 1000µg/ml and the most affected isolate of E.faecalis was no. 3 which its MIC was 64µg/ml and MBC was 128 µg/ml, while the most affected isolate of E. faecium was no. 1 which its MIC was 128 µg/ml and MBC was 256 µg/ml . Conclusion:L. fermentumCFS showed significant activity against both Enterococcus isolates and showed closely related results. Keywords: Lactobacillus fermentum , Antibacterial activity , Antagonstic
Keywords
Lactobacillus fermentum; antibacterial activity; Antagonstic effect; Enterococcus faecium; Enterococcus faecalis; vaginosis; Enterococcus faeciumEnterococcus faecalis

Statistics Article View: 188 PDF Download: 117