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Increased Frequency of Complement C4 "Null" Alleles in Autoimmune Hepatitis | ||
| Journal of the Faculty of Medicine | ||
| Article 1, Volume 51, Issue 3, 2009, Pages 304-307 | ||
| Authors | ||
| Eman S. AL-Obeidy; ; | ||
| Abstract | ||
| Summary: Background: Human leukocyte antigen (HLA) is the most polymorphic genetic system in man. The genes of this region influence susceptibility to certain diseases. Patients and methods: Immunofixation test is the method used to asses C4 polymorphism of 100 blood samples of 60 AIH patients and 40 healthy normal controls. Results: An increased frequency of C4A*Q0 was observed for patients group versus control group with P-value (0.003). Conclusions: This finding demonstrated that C4A*Q0 might play a role in AIH susceptibility. Key words: autoimmune hepatitis, HLA, C4A*Q0, Immunofixation test. | ||
| Keywords | ||
| autoimmune hepatitis; HLA; Immunofixation test | ||
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