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Isolation of Cryptococcus neofrmans from pigeon dropping and study of some pathogenesis aspects | ||
| journal of kerbala university | ||
| Article 1, Volume 4, Issue 4, 2008, Pages 316-321 PDF (0 K) | ||
| Abstract | ||
| This study was conducted to isolate and identification of C. neofrmans from fecal samples of pigeon. C. neofrmans identified by biochemical tests .Fifty white Swiss mice were used to study the gross lesion and histopathological changes of tissue. Thirty mice were inoculated S.C. with 0.5 ml of yeast suspension contain 3X 106 ; yeast cells. Twenty mice were used as control. Three mice were killed from treatment group and one mouse from the control group in different days. The respiratory signs were recorded in day while the nervous signs recorded in last days of the experiment. The yeast was isolate from liver, lung and brain during the experiment period and these organs were used to study grossly and microscopically. The gross lesions include congestion of internal organs and presences of necrotic aeries in lungs and liver and sever swelling in inoculated site. the histopathological changes includes congestion of blood vessels in livers and lungs with infiltration of inflammatory cells and formation of granulomatous lesions, while in brain we notes cavitations and miled infiltration of inflammatory cells. | ||
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