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Synthesis and Studies The Biological Activity of New Azo Compounds | ||
| journal of kerbala university | ||
| Article 1, Volume 7, Issue 1, 2011, Pages 75-83 PDF (0 K) | ||
| Authors | ||
| Zeinab N.M; Hamid H. M; Istabraq M. A | ||
| Abstract | ||
| The cyclohexanone was subjected to Hantzsch synthesis by treating with iodine and thiourea to give an intermediate 2-amino-4,5,6,7- tetrahydrobenzothiazole. This was then diazotized and coupled with various phenols and naphtholes derivatives to give a series of new disperse dyes. These azo derivatives were characterized by spectral methods 1HNMR , FT-IR, UV-VIS.. These derivatives were tested against three microorganisms Klebsiella, Pseudomonas aeuroginosa and Escherichia Coli. Some of azo compounds was slightly and non active while azo-2-naphthol was highly acive against all the bacteria species tested. | ||
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