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The Effect of Renal Hemodialysis on Serum Endogenous Antioxidants Defense of Patient with Chronic Renal Failure | ||
| Journal Of Wassit For Science & Medicine | ||
| Article 1, Volume 6, Issue 1, 2013, Pages 45-58 | ||
| Authors | ||
| Akdas Mohammed Sfaih AL-Ta; Jafar Abbas Issa Al- Maamori | ||
| Abstract | ||
| Hemodialysis means removes waste and excess fluid from the blood when thekidneyscannot do so sufficiently usually performed three or more times a week for 4 hours or more.The present work was aimed to investigate the effect of renal hemodialysis on serum anenzymatic and non-enzymatic endogenousantioxidantsdefenses. Forty five patientswere taken for this study, 25males (55.54%) with age range (11-70) years and 20 females (44.46%) with age range (6-65)years, while the subjects of control group was thirty five individuals non-undergoing hemodialysis treatment, 23 males (65.71%) with age range (15-65) years and 12 females (34.29%) with age range (18-62) years. The present results showed highly significantly decrease (p<0.05) in serum enzymatic endogenous antioxidant (catalase) andnon-enzymatic antioxidants (transferrin and bilirubin), while serum non enzymatic antioxidant uric acid showed highly increase (p<0.05) in patient with chronic renal failure.In conclusion, the present data showed that patients with chronic renal failure (CRF) undergoing hemodialysis treatmenthave physiological disturbances in both serum enzymatic and non-enzymaticendogenous antioxidants levels in all age ranges may be related to oxidative stress by renal failure disease. | ||
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