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The effect of smoking, age and infection with Helicobacter pylori on immunoglobulin’s IgG,IgM | ||
| journal of kerbala university | ||
| Article 1, Volume 7, Issue 2, 2011, Pages 193-203 PDF (0 K) | ||
| Abstract | ||
| The aim of this study was to shed more light on the change in the levels of immunoglobulin’s IgG, IgM to the peoples who infected with Helicobacter pylori as well as, knowledge of the relationship between infection and smoking and their impact on Immunoglobulin’s levels ,the current study included 45 people of gastric ulcers who have undergone screening endoscopy , as well as16 people (apparently healthy) and considered as a group to study the control of where the samples were collected from a hospital Al-Husseini education in the province of Karbala (unified theory) during the time period from 1/11/2010 until 1/4/2011. 1. The results showed the presence of a significant reduction (P <0.05) in the concentration of immunoglobulin IgG in the serum in the last three age groups (70-61) (60-51) (50-41) years with an average concentration 753.76 mg / d. L 559.01 mg / d. L 430.94 mg / d. L, respectively, compared with the control group, while the decline was not significant in age groups (40-31) (30-20) years compared with the control group. 2. The level of IgM is moral (P <0.05) for the age group I (30-20), reaching level of 125.54 mg / d. Liter, compared with the control group returned in the fall, while insignificant in the second age group (40-31) and takes the focus of IgM decline gradually with age is significant among the three age years (70-61) (60-51) (50-41) and between group control to reach 76.84 mg / d. liter and 44.55 mg / d. liter and 29.94 mg / d. liters. 3. The results of measuring the level of immunoglobulin IgG in sera of smokers a significant decrease in smokers low and middle-smoking and smoking as well as hard and who have reached the average concentration of 695.26 IgG mg / d. L and 662.33 mg / d. L and 745.44 mg / d. Liter, compared with the control group. sera were examined for the 45 peptic ulcer patients and 16 healthy control to detect IgG and IgM antibodies specific for the local solute of H. pylori by signal radical immune diffusion . 4. The results showed that the decline in the concentration of IgM was significantly in smokers are average and smoking heavily, which amounted to 78.20 mg / d. Liter and 76.33 mg / d. Liter while not noticed a significant difference in the levels of immunoglobulin IgM and among smokers low and the control group as was 109.74 mg / d. liter compared with the control group. 5.The results showed a significant decrease (P <0.05) in the levels of immunoglobulin’s supplements and immune serum in smokers and people living at the same time, compared with the control group(non infected-non smokers people) . | ||
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