Effect of Lead acetate on the histological structure  of liver , kidneys and spleen in white rats Rattus rattus

	Effect of Lead acetate on the histological structure of liver , kidneys and spleen in white rats Rattus rattus
journal of kerbala university
Article 1, Volume 7, Issue 2, 2011, Pages 238-245 PDF (0 K)
Abstract
This study was conducted on 30 male rats Rattus rattus to study the effect of Lead acetate on the histological structure of liver , kidneys and spleen of treated animals . The results showed that the liver tissues were normal in the treated animals at the dose of 30 mg / kg . for a period of 50 days of oral intubation , whereas there was a clear degeneration of liver tissue in treated animals at the dose of 40 mg /kg for 50 days of oral intubation compared with control group . The kidneys of treated animal at a dose of 30 mg / kg for 50 days of oral intubation showed marked bleeding in the cortex whereas those treated with 40 mg / kg for 50 days of oral intubation showed bleeding and vascular congestion which were more marked in the cortex compared with the kidneys of the control group . As to the spleen of treated animals with 30 mg/kg for 50 days of oral intubation there was a slight increase in the size of white pulp, whereas those treated with 40 mg / kg for 50 days of oral intubation showed a clear increase in the size of white pulp and a degeneration compared with control group .

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