Evaluation of Chlamydia Trachomatis Antibodies In Women with Infertility

K. Ismail, May

	Evaluation of Chlamydia Trachomatis Antibodies In Women with Infertility
Al-Mustansiriyah Journal of Science
Article 1, Volume 23, Issue 3, 2012, Pages 21-28
Author
May K. Ismail
Abstract
The obligate intracellular gram negative bacterium Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen worldwide, especially among young adults; infection with this agent can be asymptomatic in 80% of women, which can make diagnosis and detection of the bacterium difficult. The sequelae of undetected and thus untreated infections like acute salpingitis and pelvic inflammatory disease (PID) lead not only to significant morbidity but far more importantly to infertility. Fifty-two of infertile women (duration of infertility was approximately 1-15 years) with age ranged between (25-40) years (30 ± 4.12) and 50 of both unmarried women and mothers with age ranged between (10-30) years (28.6 ± 5.34) were studied for their antichlamydial antibodies levels using enzyme linked immunosorbent assay (ELISA). The study showed significant increase in serum IgM, IgG, IgA levels (P< 0.05) in (42.3%), (25%), (3.8%) respectively of infertile women as compared to control group; while the prevalence of antibodies in control were(10%), (4%), (2%) for IgM,IgG and IgA respectively. Also there was a high positive relation between these antibodies levels and the age of the range of (28-32) years in infertile women. The study showed high levels of C.trachomatis antibodies in both infertile and unmarried women also; we suggest that routine screening programs for C.trachomatis are needed to prevent the development of reproductive sequelae for women before marriage
Keywords
Chlamydia trachomatis; women infertility; antichlamydial antibodies; ELISA

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