Influence of oral zinc sulphate supplementation on the development of the teeth and jaws of growing rat (Histological study)

Y. Alhijazi, Athraa; H. Al-Bayati, Dhuh

	Influence of oral zinc sulphate supplementation on the development of the teeth and jaws of growing rat (Histological study)
Journal of baghdad college of dentistry
Article 1, Volume 23, Issue 0, 2011, Pages 53-58
Authors
Athraa Y. Alhijazi; Dhuh H. Al-Bayati
Abstract
Background: This study was carried out to determine the effect of oral zinc supplementation on the growth of molar teeth and jaws on growing rat. Materials and methods: Fifteen western albino pregnant rats subjected to zinc deficiency diet from time of 16th of gestation till day 21 postnatal days. Oral Zinc supplement in different dose (o.25 and o.5 mg) were added to the normal zinc diet of the mothers from one day to 21 day postnatal periods). Neonate rats were sacrificed at the followings postnatal periods ( 7, 10, 14, 18 and21 day) .Histological evaluation for the development of 1st molar tooth with development of the jaws were estimated under light microscope .In addition ,serum zinc level in all studied periods were determined with atomic absorption spectrophotometer. Results: Histological examination for experimental group(0.5) showed acceleration in the growth of molar teeth and the bones of the maxilla and mandible illustrates in early apposition of dental hard tissue and bone trabeculea. Declination in zinc levels were observed approximately in all studied groups with the increment of the period of the growth. Conclusion: This study was illustrated that there are obvious effects of oral supplementing zinc on the growth of teeth and jaws of the rat suffered from zinc deficiency in gestation period and ameloblast showed to be the most affected dental cells
Keywords
Zinc; molar teeth and jaws; Neonate rats

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