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Dental caries and salivary lipid soluble vitamins among group of women aged 30-39 years with breast cancer | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 24, Issue 1, 2012, Pages 85-89 | ||
| Authors | ||
| Basma A.Kanan; Ban S. Diab | ||
| Abstract | ||
| Background: Breast cancer is one of the serious diseases affect women in large percentage that may cause general systemic changes, these systemic changes affect on saliva composition especially lipid soluble vitamins (A ,D ,E ,K) which lead to an adverse effect on oral health status. This study were conducted to evaluate the concentration of lipid soluble vitamins (A, D, E, K) in saliva and their relation to dental caries among breast cancer and compared to control group. Materials and Methods: The total sample composed of 60 females aged 30_39 years attending Al_Yarmook Teaching Hospital, 30 females newly diagnosed with breast cancer at stages II and III before taking any treatment and surgery and 30 female without clinical signs of breast cancer (control group).The diagnosis and recording of dental caries was through the application of DMFS index according to criteria of Manji et al (1989). Salivary sample were collected under standardized condition, stimulated salivary samples were collected according to(Tenovuo and Lagerlöf, 1994) and saliva analyzed for estimation of lipid soluble vitamins (A ,D ,E ,K) by using high performance liquid chromatography (HPLC) apparatus. Results: The percentage of dental caries occurrence was 100% among breast cancer group and control group. Aries experience (DMFS) was higher among breast cancer group (45.10±17.06) compared with control group (33.63±11.10) with no significant differences. Lipid soluble vitamins (A ,D ,E ,K ) were lower in breast cancer group compared to control group with highly significant differences. Salivary lipid soluble vitamins A and E showed a not significant correlation in negative direction with dental caries experience (DMFS), while salivary lipid soluble vitamins D and K showed a not significant correlation in positive direction. Conclusions: Dental caries revealed higher percentage of occurrence among breast cancer group | ||
| Keywords | ||
| Breast cancer; dental caries; High Performance Liquid Chromatography | ||
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