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Chromosomal abnormality in couple with repeated abortion | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 1, Issue 181, 2012, Pages 48-53 | ||
| Authors | ||
| Muna A. Kashmoola; Ahmed Jasim AL-Hassanee; Sada Jasim Abdulameer | ||
| Abstract | ||
| objective: A proportion of cases with repeated abortion are caused by chromosomal abnormality in one or both parents. Several studies have been done to determine the role of chromosomal abnormalities in couples with repeated fetal loss in various countries. The aim of this study was detection of chromosomal abnormalities in couple with repeated abortion . Subjects and Methods: Cytogenetic study was done for 50 Iraqi couples who presented with repeated abortion at the Medical Center In Mosul Medical College .It was done in a private lab.Cells were studied using lymphocyte culture technique arrested at G- metaphase. Results: We found that the percentage of chromosomal abnormalities was (6%). It was not significantly different from that reported worldwide. The nature of these abnormalities were : first case 46, XX,t(5;X)(q35;q23-q25) ,second case 46XY,add(15)(p12) and the third one 46,XY,del (16)( q21). Conclusion: This study should help physicians working in the region to realize the contribution of chromosomal abnormalities as one of the causes of repeated fetal loss. It should also help in setting priorities of cytogenetic screening individual cases. | ||
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