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Influence of Metformin Administration on a Modification of TSH, T3 And T4 Level In Women With Polycystic Ovarian Syndrome | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 23, Issue 4, 2012, Pages 21-28 | ||
| Author | ||
| Qais Ahmed Ibraheem | ||
| Abstract | ||
| Metformin is the most widely used drug for the treatment of type 2 diabetes mellitus worldwide. In women with polycystic ovarian syndrome (PCOS), long-term treatment with metformin may increase ovulation, improve menstrual cyclicity, and reduce serum androgen levels. In this study thirty five PCOS patients were involved. The blood samples were obtained at the beginning before starting treatment and then metformin tablets for three months were given and then other blood samples were taken to determined T3, T4 and TSH. Our Results show a non-significant elevation in T3 and T4 levels after treatment, while TSH level was reduced high significantly after treatment compared with that before treatment. So Metformin can be used as an adjunct for the treatment of patients with thyroid cancer and Subclinical hypothyroidism. | ||
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