Serum insulin like growth factor-I  and Inhihbin B levels in patients with polycystic ovarian syndrome

M. Majeed, Bushra; A. Saleh, Rafal

	Serum insulin like growth factor-I and Inhihbin B levels in patients with polycystic ovarian syndrome
Medical Journal of Tikrit
Article 1, Volume 18, Issue 182, 2012, Pages 126-133
Authors
Bushra M. Majeed; Rafal A. Saleh
Abstract
Design: A cross section study the relationship between serum inhibin B level and Insulin Growth Factor I level, and the fertility outcome in Polycystic Ovarian Syndrome women. Setting: The study conduct at Tikrit Teaching Hospital, Department of Obstetrics and Gynecology between May 2010- May 2011. Patient: Ninety women participate with study they were included in one of the following groups: Group A: includes fifteen normal fertile women. Group B: includes fifty infertile Polycystic Ovarian Syndrome women Group C: includes twenty five fertile Polycystic Ovarian Syndrome women. Polycystic ovary syndrome is diagnosed according to the ESHRE/ ASRM Rotterdam criteria for Polycystic Ovarian Syndrome 2004. Methods: Clinical, anthropometric measurements, ultrasound study and laboratory determinations of Leutanizing Hormone, Follicular Stimulating Hormone, Prolactin, inhibin B, Insulin like Growth Factor I. Results: Serum inhibin B decreased in older infertile Polycystic Ovarian Syndrome women than fertile Polycystic Ovarian Syndrome women. Infertile Polycystic Ovarian Syndrome women have higher serum Insulin like Growth Factor I and Inhibin B than fertile PCOS and control group. Conclusion: Infertile Polycystic Ovarian Syndrome women associated with elevated serum inhibin B and serum Insulin like Growth Factor I levels.

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