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The genotoxic effect of chloroform on the white mouse Mus musculus L. | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 17, Issue 3, 2012, Pages 55-59 | ||
| Authors | ||
| Omar R. khalaf; Adil F. Shihab | ||
| Abstract | ||
| This study included investigating the genotoxic effect of chloroform on males and females white laboratory mice, Mus musculus strain Balb/c. Results showed that chloroform has the ability to motivate chromosomal aberrations represented by chromatid break , and centromore break in somatic cells for both males and females , Results also revealed significant differences in chromatid break for both male and females mice , injected with the concentrations 0,025 & 0,05 mg/25 g body weight when compared with control group , It was found that there were asignificant differences in centromore break of females, injected with two concentrations of chloroform in comparison with control group , while no significant differences were observed in males .The concentration 0,05 mg/25 g was more influential in comparison ,with the concentration 0,025 mg/25 g . It was found that 30 days of injection is more influent in comparison with 15 days of injection ,and males are more influenced than females . | ||
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