Histological Experimental Study To Diagnosis Acute, Chronic And Congenital Infections Of Toxoplasmosis Among Aborted And Normally Delivered Women in Mosul City

	Histological Experimental Study To Diagnosis Acute, Chronic And Congenital Infections Of Toxoplasmosis Among Aborted And Normally Delivered Women in Mosul City
Tikrit Journal of Pure Science
Article 1, Volume 18, Issue 1, 2013, Pages 17-22
Abstract
This study was conducted during the period from May 2007 to August 2008 to investigate the histopathological changes that occur due to the infection with Toxoplasma gondii parasite among aborted and normally delivered women in Mosul City attending to AL-Khansa`a educating hospital for maternity and children. Out of 150 women under study group , 50 were aborted while the other 100 were normally delivered women , the parasitic infection was found in 28 placenta (56%) from overall 50 aborted placenta, and found in 57(57%) from overall 100 non aborted placenta by the use of direct microscopic examination test of homogenized histological suspension smear stained by Gimsa or Lieshman`s stains , these suspension were also injected in the peritoneal cavity of laboratories experimental Balb/c mice , infection was recorded in 41 mice (82%) that injected by placental suspension of aborted women and 18 mice (18%) were inoculated by the placental suspension of normally delivered women , the histological section were prepared from both infected placenta and laboratories experimental mice organs to study the histopathological changes that results from the infection were represented by necrosis, vaculation and cells degeneration , inflammatory cells infiltration and the focal inflammatory reaction in addition to hemorrhage and accumulation of eosinophilic substances . Another method was used for the diagnosis by injected 50 blood samples taken from aborted women and 200 blood samples taken from mother and embryo cord blood of normally delivered women in peritoneal cavity of laboratories experimental mice, the infection rate was found in (16%) in mice that injected by the blood samples taken from aborted women, while the infection rate was found in( 12%) ,( 16%) in mice injected by the blood samples taken from mother and embryo cord blood respectively.

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