Isolation of some dermophytes from human and study the effect of some plant extract and antifungi on them

A.A. Alssadi, Hussen; I.Bander, Khalil; A.Hamada, Thikra

	Isolation of some dermophytes from human and study the effect of some plant extract and antifungi on them
Tikrit Journal of Pure Science
Article 1, Volume 18, Issue 1, 2013, Pages 29-39
Authors
Hussen A.A. Alssadi; Khalil I.Bander; Thikra A.Hamada
Abstract
109 skin mycotic samples were collected in 2011 from July to November for isolation and identification fungi The direct microscopic investigation showed 84 positive samples in 77% ratio from total patients were represented in 25 case about 22.9% the laboratory culture results have shown 75 positive samples in 68.8% and 34 negative samples in 31.1%. These samples included skin scrapping, hair fragments, nail clippings from humanIn respect with human samples, there were 75 fungal species isolated and identified and the genus Trichophyton was more frequent (61.3%), than Microsporum (25.3%) and the Pidraia hortae was isolation in 9 sample(12%). Females were the more infected (64.21%) than males (35.79%). In addition, the Tinea capitis were the most infected (34.8%) when compared with other body regions. The results of the present study showed the Garlic and Zengiber aqueous and alcoholic extracts have high suppressive effect against T.mentagrophytes, Pidraia hortae and M.ferrginum in (6 , 10 ,12 ,13)mg/ml and these extracts have variable effects on fungi . The relatio ship between them is venatically that mean the extract suppression effect will increasing. The aqueous and alcoholic extract of Zengiber did not inhibit Pidraia hortae growing. The antifungal drugs ketoconazole , Terbinafine and Grisofulvin have inhibitory effect against the isolated fungi and in different concentration depending on fungi type and the antifungal type ,the minimum inhibitatory concentration to antifungal substances is (0.4)mg/ml.

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