Autoimmune Haemolytic Anemia Associated

Mohammed Jasim, Amany

	Autoimmune Haemolytic Anemia Associated
Al-Mustansiriyah Journal of Science
Article 1, Volume 23, Issue 6, 2012, Pages 43-52
Author
Amany Mohammed Jasim
Abstract
The present study, extended from July 2011 to November 2011, a total of seventy two samples were collected from individuals their ages ranged from 16- 70years forty two was anaemic patients( 16 males and 26 females) with chronic myelocytic leukemia(CML), acute lymphoblastic leukemia( ALL), chronic Lymphocytic leukemia (CLL), Hodgkin lymphoma (HL), non-Hodgkin lymphoma( NHL) and rheumatoid arthritis (RA). Other thirty samples were collected from non anaemic individuals as control group( 10 males and females). All samples were tested by anti-human globulin (Coomb’s test), Preparation of blood film and Radial Immunodiffusion (RID) . It was observed that female more susceptible than male to the Auto immunhemolytic anemia(AIHA) ,no significant differences were noticed in the ages of AIHA patients compared with the control group. AIHA who gave positive coombs test( DAT ), CML anemic patients had a higher AIHA percentage (47.62%),while HL patients had the lower percentage (4.76%).the incidence of+veRH blood grouping of anemic patients with AIHA presented in this study was more susceptible to AIHA than –ve RH anemic patients. The distribution of blood grouping system was shown that blood group B (33.33%) was more susceptible to the AIHA than other groups. The results of precipitation reaction of IgG, IgM, IgA class and C3,C4 using immnodiffusion techniques. It was observed that the mean result of C3 had a highly result of precipitation reaction among anemic patients with AIHA according to the normal averages of WHO (2003) It also documented that autoimmune hemolytic anemia was strongly associated with increased risk of CLL among anemic patients studied.

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